Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC HY-141520 10mg , ART558 CAS:2603528-97-6 Purity:>98%
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HY-141520 10mg ART558 CAS: 2603528-97-6 ART558 is a nanomolar potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Z-Yvad-Fmk 1Mg | HY-P1009-1MG
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Z-Yvad-Fmk 1Mg
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Medchemexpress LLC 2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide | 1698878-14-6 | MFCD28963946 | 99.5% | C20H25N3O5S | 10MG
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Nampt-IN-1 (LSN3154567) is a potent, selective inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) used in research to study NAD+ biosynthesis, metabolism, and anticancer mechanisms. It inhibits purified NAMPT with an IC50 of 3.1 nM and has been characterized in vitro and in vivo for pharmacokinetics and biological activity.
- Potent, selective NAMPT inhibition (IC50 = 3.1 nM).
- Characterized in vitro and in vivo for pharmacokinetics and activity.
- Useful for cell-based assays probing NAD+ metabolism and proliferation.
- Supplied as a high-purity research-grade powder suitable for biochemical studies.
- Documented oral exposure and toxicity profiles in animal models for translational research.
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Selleck Chemical LLC VL285 S0095-25MG
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VL285 is a potent VHL ligand that degrades HaloTag7 fusion proteins Cotreatment with excess VL285 the core VHL ligand from which HaloPROTAC3 is derived is able to significantly reduce HaloPROTAC3 mediated activity to 50% degradation
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Medchemexpress LLC HY-12702 10mg , 10058-F4 CAS:403811-55-2 Purity:>98%
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HY-12702 10mg 10058-F4 CAS: 403811-55-2 10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Rezivertinib E4675-1G
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Rezivertinib(BPI-7711) is a potent third-generation inhibitor of EGFR tyrosine kinase targeting both EGFR-sensitizing mutations and the EGFR T790M mutation Additionally it has excellent CNS penetration and has antitumor activity
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Selleck Chemical LLC MIRA-1 E4634-5MG
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MIRA-1(NSC 19630) a maleimide compound is a selective inhibitor of Werner syndrome WRN helicase activity with an IC50 of 20 M while sparing ATPase and exonuclease activities It reactivates mutant p53 inducing apoptosis in various human solid tumor cell lines with tetracycline-regulated mutant p53
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Selleck Chemical LLC Darifenacin E6020-100MG
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Darifenacin [( )-UK-88525] is a potent specific and competitive M3 selective receptor antagonist (M3 SRA) that has been shown to have high affinity and selectivity for the M3 receptor It significantly improves major overactive bladder (OAB) symptoms with proven efficacy tolerability and safety
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Sigma Aldrich Fine Chemicals Biosciences Zaprinast solid | 37762-06-4 | MFCD00214073 | 100MG
Zaprinast solid | Mol Wt: 271.27 | 37762-06-4 | MFCD00214073 | 100MG
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Medchemexpress LLC Khellin | 82-02-0 | 99.7% | 25 MG
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Khellin is a furochromone isolated from *Ammi visnuga L.* that functions as an EGFR inhibitor with an IC50 of 0.15 μM. It exhibits anti-proliferative activity in vitro and possesses antispasmodic and coronary vasodilator effects.
- Acts as an EGFR inhibitor
- Demonstrates anti-proliferative activity in vitro
- Possesses antispasmodic and coronary vasodilator effects
- Inhibits Ca2+ influx pathways
- Soluble in DMSO at 16.67 mg/mL
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Cayman Chemical ANTIBODY 2-thIo PAF 5mg
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A PAF receptor agonist with potency comparable to PAF C-18 and PAF C-16; chromogenic substrate used in Cayman’s PAF-AH Assay Kit (Item No. 760901)
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Sigma Aldrich Fine Chemicals Biosciences ICRF-193 apoptosis inducer, arabinosidase substrate | 21416-88-6 | MFCD01702964 | 1MG
ICRF-193 apoptosis inducer, arabinosidase substrate | Purity: >=95% | Mol Wt: 282.3 | 21416-88-6 | MFCD01702964 | 1MG
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TARGETMOL CHEMICALS INC R162 10MG
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor. purity: 97%
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Medchemexpress LLC Phospho-CDK1 (Tyr15) Antibody | 10 UL
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Phospho-CDK1 (Tyr15) Antibody is a rabbit-derived, non-conjugated IgG polyclonal antibody designed for research applications. It specifically targets Phospho-CDK1 (Tyr15) and is suitable for use in Western Blotting experiments. This antibody is affinity purified and reactive with human, mouse, and rat samples.
- Rabbit-derived polyclonal antibody
- Targets Phospho-CDK1 (Tyr15)
- Reacts with human, mouse, and rat
- Affinity purified
- Suitable for Western Blot (WB) applications
- Supplied in PBS (pH 7.3), 50% glycerol, and 0.5% BSA with 0.02% sodium azide as a preservative
- Predicted and observed band size of 34 kDa
- Stored at -20°C for 1 year
- Ships with blue ice
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Medchemexpress LLC GNE-8505 1mg | 1620573-48-9 | 1 MG
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GNE-8505 is an orally available small-molecule inhibitor of dual leucine zipper kinase (DLK, MAP3K12) used in preclinical research to inhibit DLK signaling and downstream JNK phosphorylation. Supplied as a high-purity, white to off-white solid for laboratory research use only.
- Orally active dual leucine zipper kinase inhibitor
- High purity: 99.86%
- Molecular formula C21H24F3N5O, molecular weight 419.44 g/mol
- White to off-white solid powder
- Storage: powder -20°C (3 years), 4°C (2 years)
- For research use only, not for human or veterinary use
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